In 1750 Jean de Gères inherited the vineyard, then was succeeded by Jean-Jacques de Gères, who in turn left it to his daughter, Jeanne; she wed François de Carles, whose family settled in the Bordeaux region from their native Lorraine in the 14th century.
Under the guidance of the illustrious de Carles family, between 1682 and 1826 the domain enjoyed a long period of improvements during which Monbousquet developed a remarkable heritage and history.